Two New C₂₁Steroidal Glycosides from Selaginella Braunii Baker

Abstract Two new C21 steroidal glycosides, brapreguanes A and B ( 1 – 2 ) were isolated from 75 % aqueous ethanol extract of Selaginella braunii Baker. Their structures were established by spectroscopic analyses (1D/2D NMR spectra and HR‐ESI‐MS). The absolute configurations of sugar were elucidated by enzymatic hydrolysis and GCMS analysis. In addition, all compounds were evaluated for the anti‐proliferative activities against various human cancer cells in vitro . Compounds exhibited no inhibition to various human cancer cells.