アンケートを用いた市中歯科医師の薬剤耐性対策アクションプラン認知度による内服抗菌薬の使用動向と薬剤師とのかかわりに対する実態調査

Considering the current situation of serious antimicrobial resistance, a national action plan on antimicrobial resistance (AP) has been passed in Japan. As it is essential to determine the extent to which dentists are aware of AP, a mail-based questionnaire survey regarding recognition of the AP was performed by targeting dentists in Sapporo city. The response rate for this questionnaire was 36.1％ (356/985). The results indicated that azithromycin is prescribed by dentists who recognize the AP (odd ratio (OR) = 1.75 (95％ confidence interval (CI): 1.03 - 2.95), P = 0.04). Simultaneously, dentists who do not recognize the AP choose antimicrobials based on the knowledge obtained at lectures in a university (OR = 0.23 (95％ CI: 0.10 - 0.51), P < 0.01) and faropenem is prescribed by dentists who do not recognize the AP (OR = 0.13 (95％ CI: 0.03 - 0.68), P = 0.02). Dentists who did not issue out-of-hospital prescriptions constituted 79.8％ (281/352), suggesting that dental doctors may hardly have any relationship with pharmacists. It is thus necessary to enhance coordination between dentists and pharmacists for promoting the proper use of antimicrobials.