Effect of denosumab on osteoclast activity of osteolytic lesions after total hip arthroplasty: a proof of concept trial

Mahatma Mohit,Jayasuriya Raveen, Fatma Gossiel, Gallagher Orla,Hughes David, Buckley Simon,Gordon Andrew, H Schmidt Andrew, Tomouk Mohammad,Wilkinson Jeremy Mark

Orthopaedic Proceedings（2021）

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摘要

Abstract Objective In this phase 2 clinical trial (EudraCT 2011-000541-20) we examined the effect of denosumab versus placebo on osteolytic lesion activity in patients undergoing revision surgery a...

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关键词

denosumab on osteoclast activity,osteolytic lesions,total hip arthroplasty,hip arthroplasty

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