Amount of Recurrence Following Surgical Repair of Non-syndromic Craniosynostosis at Single Center

Research Square (Research Square)(2021)

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Abstract
Abstract Background: Craniosynostosis is a deformity of the skull that occurs as a result of early fusion of one or more cranial sutures and can be accompanied by neurological deficits. Craniosynostosis can be classified as syndromic or non-syndromic according to the type of suture involved. Surgical treatment of craniosynostosis in infants basically involves loosening and opening the fused sutures to reduce intracranial pressure, allow the brain to grow, and also fix the skull shape. However, in such cases there is a risk of re-synostosis after surgery. According to the literature, re-synostosis rates vary between 0% and 70%. In this study, we aimed to evaluate the re-operation rate in craniosynostosis cases treated surgically in our clinic.Methods: A retrospective analysis of 70 non-syndromic craniosynostosis cases treated surgically in the Neurosurgery Department of Bursa Uludag University from 2005–2019 was performed. All patients had undergone total cranial vault remodeling surgically and had been followed up for at least a year.Results: The study group included 70 patients, comprising 40 (57.1%) male and 30 (42.9%) female patients. The mean age of the group was 10.9 ± 7.8 months (range 3–34 months). Out of 70 patients, repeat surgery due to re-synostosis had been performed once in 5 (7.1%) patients and twice in 1 (1.4%) patient.Conclusion: Early identification and prompt referral play a very significant role in the management of patients with craniosynostosis. Further studies based on a larger sample size are recommended for more quantitative data and better results.
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Key words
surgical repair,non-syndromic
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