Association of Patient Characteristics with in Vitro Fertilization (IVF) Failure in Graha Amerta Fertility Clinic Dr. Soetomo General Hospital, Surabaya

Background : Due to the development of science and technology in the field of medicine, infertility has been solved by the discovery of one of the most sophisticated ART program, known as IVF.Although this procedure has been carried out for more than 40 years, the failure rate is still very high.This problem is considered to be related with the characteristic of the patient undergoing IVF.This study aims to determine the association between patient's multi-characteristics and IVF failure.Method : This research is an observational analytic research with cross-sectional method.The determination of the research sample uses a total sampling technique by taking all members of the population in accordance with the conditions.Result : Out of 102 couples undergoing IVF, 37 couples (36,3%) successfully obtained a pregnancy while the 65 other couples (63,7%) failed IVF or has not obtained a pregnancy.The result of the p value between IVF failure and maternal age is 0,03, with BMI 0,532, with sperm quality 0,577, with PCOS 0,297, with endometriosis 0,578, and with POR 0,027. Conclusion :Out of all the studied patient characteristics, only maternal age and POR are associated with IVF failure with the p value of 0,03 and 0,027 respectively.BMI, sperm quality, PCOS, and endometriosis do not show a significant correlation with IVF failure.