Interaction between uric acid and obesity

Background: Hyperuricemia is associated with a diversity of other illnesses comprising increased alcohol and purine-rich food ingestion and obesity. Hyperuricemia is deliberated to be a lifestyle condition interrelated with obesity. Objective: The aspire of this revision was to assess the occurrence of hyperuricemia and its association with obesity among Iraqi adults. Subjects and Methods: Ninety participants with hyperuricemia participated in this study; their ages ranged from 35 to 50 years. They were classified into two groups: obese (n = 45) and nonobese (n = 45) from January 2019 to July 2019 at Medical City Hospital/Baghdad. Results: There was a substantial rise (P < 0.05) in body mass index (BMI), fasting serum glucose (FSG), total cholesterol (TC), triacylglycerol (TAG), and low-density lipoprotein cholesterol, while there was a substantial reduction in serum high-density lipoprotein cholesterol (HDL-C) in obese subjects as paralleled to nonobese. Furthermore, there was an elevation in serum lipid ratios, but they were not significant. A substantial rise in serum uric acid was found in obese subjects as paralleled to nonobese. An elevation in serum uric acid level was found in males as paralleled to females, but it was not substantial. Furthermore, there was a substantial positive correlation between serum uric acid and BMI, waist circumference, waist-to-hip ratio, FSG, TC, TAG, and low-density lipoprotein cholesterol, while there was a significant negative correlation between serum uric acid and HDL-C in obese subjects. Conclusions: Outcomes of this data designate a substantial positive correlation between hyperuricemia and obesity among Iraqi adult subjects. Thus, routine measurement of serum uric acid is suggested in obese persons to avoid hyperuricemia and its associated problems.