Green Solvents for Analytical Chemistry

This chapter gives an overview of available green solvents that could be applied in extraction as a sample preparation method prior to analysis. Examples of replacements of petroleum solvents are given to illustrate successes in using solvent-free systems, water, super- or subcritical fluids, ionic liquids, deep eutectic solvents and bio-based solvents. A survey is also presented of existing tools used as decision-making aids for the selection of one or more solvents according to the target molecules, especially HSPiP software programs (based on Hansen solubility parameters) and COSMO-RS (Conductor-like Screening Model).