Novel Synthesis of Pyrido[2,3-b ]quinoxaline-3-carboxylate Derivatives via One-Pot Buchwald Amination-Cyclization

Majdi Hajri,Omar Khoumeri,Raoudha Abderrahim,Thierry Terme,Patrice Vanelle

SYNTHESIS-STUTTGART（2024）

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摘要

A novel series of pyrido[2,3-b]quinoxaline-3-carboxylate derivatives was synthesized in short reaction times and in moderate to good yields by using a palladium catalyst in a one-pot Buchwald amination/cyclization reaction.

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关键词

quinoxalines,nucleophilic substitutions,malonic esters,Buchwald amination/cyclization,palladium catalysis,pyrido[2,3-b ]quinoxaline-3-carboxylates

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