1,8-Naphthalimide-Based Chemosensors: A Promising Strategy for Detection of Metal Ions in Environmental and Biological Systems

The advancement of optical chemosensors has achieved success with the advent of Supramolecular Chemistry. Unlike other scaffolds, the 1,8-naphthalimide motif has emerged as an excellent fluorescent chemosensor due to its photophysical properties like thermostability, cytotoxicity, membrane permeability, selectivity, and sensitivity. The naphthalimide scaffold is distinctive in its ways of tracking biological analytes and diagnosing its role in various diseases. This review provides insight into current developments in the synthesis and designing of 1,8-naphthalimide-based chemosensors for the recognition of metal ions, its mechanistic approach for its sensitivity, selectivity, and practical applications in a real environment. We hope that this review will aid to develop a novel approach to sense toxic analytes in real water samples and improve real-time applications. Recent years have witnessed tremendous research in Supramolecular Chemistry with incredible outcomes in terms of sensitivity and the working of chemosensors. The intriguing properties of 1,8-napthalimide derivatives makes it an excellent marker for displaying vibrant potential in the field of bioinorganic chemistry, material chemistry, Analytical Chemistry, medical science communities, etc.image