[Case of Long-Term Response to Radiotherapy for Intramedullary Spinal Cord Metastasis from Ovarian Cancer after Surgery].

Shuou Sudo,Akira Torii,Natsuo Tomita,Taiki Takaoka, Ryota Horie,Seiya Takano, Nozomi Kita,Masanari Niwa,Dai Okazaki, Yuto Imai, Minori Niwa, Yusuke Nakashima, Kenshiro Osumi, Yusuke Tsuzuki, Mayu Kuno,Akio Hiwatashi

Gan to kagaku ryoho. Cancer & chemotherapy(2023)

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摘要
Intramedullary spinal cord metastasis(ISCM)often causes spinal cord neuropathy and should be treated as an oncologic emergency. However, it recurs in most cases after treatment, ISCM is a disease with a very unfavorable prognosis. Herein, we report a successfully treated case of ISCM with emergent and high-dose radiotherapy. A 53-year-old woman had difficulty walking without assistance 2 years after surgery for ovarian cancer. She received emergent radiotherapy at a total dose of 50 Gy in 25 fractions. Her neurological symptoms dramatically improved over 3 weeks after radiotherapy. ISCM has been controlled using the imaging tests at 5 years after radiotherapy. We believe that both emergent and high-dose radiotherapy were effective for ISCM.
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