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Organocatalytic asymmetric synthesis of β,β-diaryl ketones via one-pot tandem dehydration/1,6-addition/decarboxylation transformation of β-keto acids and 4-hydroxybenzyl alcohols

Jia-Pan Niu,Jing Nie,Shen Li,Jun-An Ma

Chemical Communications（2020）

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Abstract
An one-pot tandem dehydration/1,6-addition/decarboxylation transformation of β-keto acids and 4-hydroxybenzyl alcohols provides an metal-free protocol to chiral β,β-diaryl ketones.
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