Genetic loss of importin α4 causes abnormal sperm morphology and impacts on male fertility in mouse.

Yoichi Miyamoto,Mitsuho Sasaki,Haruhiko Miyata,Yoko Monobe,Masahiro Nagai,Mayumi Otani,Penny A F Whiley,Akane Morohoshi,Shinya Oki,Junichiro Matsuda,Ken-Ichi Akagi,Jun Adachi,Masaru Okabe,Masahito Ikawa,Yoshihiro Yoneda,Kate L Loveland,Masahiro Oka

The FASEB Journal（2020）

引用 12|浏览3

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摘要

Importin α proteins play a central role in the transport of cargo from the cytoplasm to the nucleus. In this study, we observed that male knock-out mice for importin α4, which is encoded by the Kpna4 gene (Kpna4 -/--/--/--/--/--/--/--/-

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