Reprogramming Captures the Genetic and Tumorigenic Properties of Neurofibromatosis Type 1 Plexiform Neurofibromas

(Stem Cell Reports 12, 411–426; February 12, 2019) In the originally published version of our supplemental information, a software processing error had caused Figure S2G to go missing. The supplemental information has now been corrected to include this missing panel and the correct version of Figure S2 is also reproduced below. We apologize for the confusion.Figure S2. iPSC Characterization of the Additional Banked NF1 iPSCs Lines, originalView Large Image Figure ViewerDownload Hi-res image Download (PPT) Reprogramming Captures the Genetic and Tumorigenic Properties of Neurofibromatosis Type 1 Plexiform NeurofibromasCarrió et al.Stem Cell ReportsJanuary 31, 2019In BriefIn this article, Eduard Serra and colleagues describe the generation of iPSCs directly from plexiform neurofibromas (PNFs), benign Schwann cell (SC) tumors associated with neurofibromatosis type 1. iPSCs bearing the double inactivation of the NF1 gene were differentiated into SCs that exhibited a high proliferation rate, a poor myelination ability, and a tendency to form spheres, resembling PNF-derived SCs. Full-Text PDF Open Access