Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells

Giuliana Magri,Michio Miyajima,Sabrina Bascones,Arthur Mortha,Irene Puga,Linda Cassis,Carolina M Barra,Laura Comerma,Aleksey Chudnovskiy,Maurizio Gentile,David Llige,Montserrat Cols,Sergi Serrano,Juan Ignacio Aróstegui,Manel Juan,Jordi Yagüe,Miriam Merad,Sidonia Fagarasan,Andrea Cerutti

Nature Immunology（2014）

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摘要

Marginal zone B cells provide rapid antibody responses to blood-borne antigens. Cerutti and colleagues identify a RORγt-dependent innate lymphoid cell subset that establishes crosstalk among multiple cell types to enhance antibody responses.

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关键词

lymphoid cells,antibody production,immunological signals

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