Intratumoral injection of Clostridium novyi -NT spores induces antitumor responses
Nicholas J. Roberts,Linping Zhang,Filip Janků,Amanda Collins,Ren Yuan Bai,Verena Staedtke,Anthony Rusk,David Tung,Myrna M. Miller,Jeffrey J. Roix,Kristen V. Khanna,Ravi Murthy,Robert S. Benjamin,Thorunn Helgason,Ariel D. Szvalb,Justin E. Bird,Sinchita Roy‐Chowdhuri,Halle H. Zhang,Yuan Qiao,Baktiar O. Karim,Jennifer S. McDaniel,Amanda Elpiner,Alexandra Sahora,Joshua L. Lachowicz,Brenda Phillips,Avenelle I. Turner,Mary K. Klein,Gerald Post,Luis A. Díaz,Gregory J. Riggins,Nickolas Papadopoulos,Kenneth W. Kinzler,Bert Vogelstein,Chetan Bettegowda,David L. Huso,Mary Varterasian,Saurabh Saha,Shibin Zhou Science Translational Medicine（2014）
摘要
Clostridium novyi -NT targets aberrant tumor physiology and can produce a precise, robust, and reproducible antitumor response.
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<i>clostridium,intratumoral injection,antitumor responses
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