Comparison of two pharmaceutical products containing ferrous sulfate using Mössbauer spectroscopy
Hyperfine Interactions(2023)
摘要
Two fresh commercial pharmaceutical products containing ferrous sulfate such as Tardyferon® and Fenules® were studied by X-ray diffraction and Mössbauer spectroscopy. The obtained results demonstrated that each product contains iron compounds assigned to (i) FeSO 4 × H 2 O and FeSO 4 × 4H 2 O in Tardyferon® and probably two FeSO 4 × H 2 O compounds with some tiny variations in the iron local microenvironments in Fenules®, and (ii) one ferric compound which was unidentified for Tardyferon® but identified as ferric acidic iron sulfate for Fenules®. A water free ferrous sulfate declared by the manufacturer was not found in Fenules®.
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关键词
Mössbauer spectroscopy,X-ray diffraction,Iron-containing pharmaceuticals,Ferrous sulfate,57Fe hyperfine parameters
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