Dieulafoy lesions: a rare entity in gastrointestinal bleeding

Abstract Text Five patients in our center presented recurrent gastrointestinal bleeding of uncertain origin, with multiple endoscopies performed. Colonic Dieulafoy lesions were finally identified in all of them. In most cases, endoscopic treatment was performed with placement of hemoclips with favorable evolution. Dieulafoy lesions represent a rare, although potentially fatal, cause of acute gastrointestinal bleeding. They constitute a diagnostic challenge because they can go unnoticed. Endoscopic hemostatic treatment has a high success and significantly reduce mortality rates. We must consider this type of lesion in the differential diagnosis of gastrointestinal bleeding. A meticulous endoscopy is essential for its diagnosis and treatment.