Orally administered Indocyanin Green for the functional assessment of the Gastrointestinal Tract by Multispectral Optoacoustic Tomography

Introduction Multispectral optoacoustic tomography (MSOT) is capable to non-invasively visualize endogenous and exogenous chromophores in various human tissues. The intravenous application of indocyanine green (ICG), a clinical approved fluorescent dye, already allows for mapping of lymphatic and vascular networks. We present a translational study, reaching from phantom experiments to a human clinical trial, for intraluminal detection of ICG for non-radiant bed-side evaluation of the gastrointestinal passage.