Drug Interaction Between Co-packaged Nirmatrelvir-ritonavir and Tacrolimus might cause Hyponatremia and Tacrolimus Intoxication in Lung Transplant Recipients

Research Square (Research Square)(2023)

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摘要
Abstract COVID-19 infection in recipients of lung transplants could be lethal owing to the immunosuppressant agents. Antiviral agents should be administered to these patients. Co-packaged nirmatrelvir-ritonavir is a new agent that is used in combination with antiviral medications. Here, we report a case of high serum tacrolimus concentration and hyponatremia after co-packaged nirmatrelvir-ritonavir administration.
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关键词
tacrolimus intoxication,hyponatremia,co-packaged,nirmatrelvir-ritonavir
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