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Immune Checkpoints Are Predominantly Co-Expressed by Clonally Expanded CD4+FoxP3+ Intratumoral T-cells in Primary Human Cancers

Delphine Bredel, Edi Tihic,Séverine Mouraud,François-Xavier Danlos,Sandrine Susini,Marine Aglave,Alexia Alfaro, Chifaou Mohamed-Djalim,Mathieu Rouanne,Héloise Halse,Amélie Bigorgne,Lambros Tselikas,Stéphane Dalle,Dana M. Hartl,Eric Baudin,Catherine Guettier, Eric Vibert,Olivier Rosmorduc,Caroline Robert,Sophie Ferlicot,Bastien Parier,Laurence Albiges,Vincent Thomas de Montpreville,Benjamin Besse,Olaf Mercier,Caroline Even,Ingrid Breuskin,Marion Classe,Camélia Radulescu,Thierry Lebret,Patricia Pautier,Sébastien Gouy,Jean-Yves Scoazec,Laurence Zitvogel,Aurélien Marabelle,Mélodie Bonvalet

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH（2023）

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关键词
Cancer,Immunology,Immune checkpoints,T-cells,Immunotherapy,Single-cell RNA-Seq,Flow cytometry,TCR repertoire
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