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"Rapid Asparagine Depletion as a Possible Risk Marker for Pancreatitis in Children with Acute Lymphoblastic Leukemia Under Treatment with L-Asparaginase: Case Report from Five Patients"

Biomedical Journal of Scientific and Technical Research(2023)

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Abstract
We will be describing our experience with five patients diagnosed with acute lymphoblastic leukemia (ALL), who developed L-Asparaginase (L-Asp)-induced pancreatitis during their remission induction stage. The patients were treated, at the State Cancer Center of Durango, Mexico (CECAN-Durango) since December 2021, along with a group of 30 pediatric patients (in the remission induction phase of their treatment) who did not develop pancreatitis.
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Key words
rapid asparagine depletion,lymphoblastic leukemia,acute lymphoblastic leukemia,pancreatitis,l-asparaginase
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