A biopharmaceutics perspective on oral peptide developability and drug delivery
Elsevier eBooks(2022)
摘要
In this chapter we discuss oral peptide delivery from a biopharmaceutics perspective to help understand how peptides and formulations can be designed to induce flux across the intestinal barrier in order to achieve systemic exposure. Considerable efforts have gone into understanding developability of small molecule compounds for oral delivery. We aim to extend these considerations to peptide candidates to help guide selection of chemical matter and formulations.
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关键词
oral peptide developability,biopharmaceutics perspective,drug delivery
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