РОЛЬ ЖЕЛЧНЫХ КИСЛОТ В РЕГУЛЯЦИИ ЛИПИДНОГО И УГЛЕВОДНОГО ОБМЕНА У БОЛЬНЫХ НЕАЛКОГОЛЬНОЙ ЖИРОВОЙ БОЛЕЗНЬЮ ПЕЧЕНИ И САХАРНЫМ ДИАБЕТОМ 2 ТИПА

Л. А. Звенигородская,А. В. Петраков,Т. В. Нилова,Г. Г. Варванина, А. Э. Лычкова

Экспериментальная и клиническая гастроэнтерология（2016）

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Abstract

Bile acids regulate glucose and lipid metabolism. Aim - determination of total serum bile acids in patients with NAFLD and in combination with type 2 diabetes. To determine the inflammatory markers (nitric oxide, endotoxin, phospholipase A2, malondialdehyde) effects role for the synthesis and transport of bile acids. NAFLD patients with type 2 diabetes observed decrease in synthesis and disruption of transport of bile acids, which is associated with the cell membrane damage by inhibition of enzyme systems, and inflammation.

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