Микроциркуляторные И Гематологические Нарушения У Детей С Врожденными Расщелинами Верхней Губы И Неба На Этапах Оперативной Коррекции

Full-thickness labial and palatal cleft defects are the commonest congenital malformations. The totality of structural and functional changes developing after birth cause disbalance in regulation of homeostasis, vascular tone, and coagulation system that are crucial for reparation of surgically damaged tissues. Microcirculation in the prolabial region of 50 patients was studied before and soon after the surgical treatment in conjunction with characteristics of the coagulation system and their variation depending on the severity of chronic stress. Correlation analysis of the degree of microcirculatory disturbances and vegetative reactivity was used to predict the aesthetic result of the treatment. A group of children is distinguished with high risk of pathological cicatrization due to acute intensification of homeostatic reactions.