Saccharomyces cerevisiaeEssential Genes with an Opi− Phenotype

AbstractThe overproduction and secretion of inositol (i.e., Opi−) phenotype is associated with defects in regulation of phospholipid biosynthesis in yeast. Here we report a screen of the essential yeast gene set using a conditional-expression library. This screen identified novel functions previously unknown to affect phospholipid synthesis.