Performance evaluation of a novel multi-pinhole SPECT system

In this work, the performance of a novel multi-pinhole SPECT (MPH SPECT) system based on Insight NM/CT Pro (Beijing Novel Medical Equipment Ltd) was evaluated. The sensitivity, spatial resolution, and quantitative accuracy of the MPH system were evaluated in conjunction with the methods in NEMA NU 1-2018. In addition, the performance of MPH in myocardial perfusion imaging was validated by phantom study and clinical study. The average sensitivity of MPH SPECT at the center, half, and edges of field of view (FOV) were 510 count s(-1) MBq(-1) (cps/MBq), 490 +/- 85 cps/MBq and 540 +/- 170 cps/MBq, respectively; the spatial resolution is about 6.5 +/- 0.7 mm, 6.4 +/- 0.8 mm, and 5.4 +/- 0.4 mm for X, Y, and Z axes, respectively; the quantitative accuracy is superior to the conventional SPECT with low-energy high-resolution collimator (LEHR SPECT). The images of the phantom study and clinical study demonstrated the MPH SPECT can take only 5 minutes to obtain myocardial images with high image quality.