Exploring the antiviral potential of justicidin B and four glycosylated lignans from Phyllanthus brasiliensis against Zika virus: A promising pharmacological approach

Ariane Coelho Ferraz,Paulo Wender P. Gomes,Marília Bueno da Silva Menegatto,Rafaela Lameira Souza Lima,Pedro Henrique Guimarães,José Diogo Evangelista Reis,Alice Rhelly Veloso Carvalho,Sônia das Graças Santa Rosa Pamplona,Abraão de Jesus Barbosa Muribeca,José Carlos de Magalhães,Consuelo Yumiko Yoshioka e Silva,Milton Nascimento da Silva,Cintia Lopes de Brito Magalhães

Phytomedicine（2024）

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摘要

•Extract from Phyllanthus brasiliensis has antiviral activity against Zika virus.•Lignans from Phyllanthus brasiliensis reduce the Zika virus load.•Promising use of Phyllanthus brasiliensis in the treatment of Zika disease.

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关键词

Justicidin B,Tuberculatin,Phyllanthostatin A,“Quebra-Pedra”,Zika, antiviral

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