A mini-invasive approach for endoscopic resection of rectal lesion involving the dentate line

Abstract Text A 50-year-old patient underwent screening colonoscopy,which showed a 30-mm-large granular LST(Kudo IIIL, JNET 2A)extending from the distal rectum to the dentate line and involving an internal hemorrhoid.To reduce the risk of bleeding, we opted for percutaneous embolization of the superior rectal arteries followed by EMR.Histology revealed a high-grade intraepithelial squamous lesion (HSIL/AIN2-3)associated with HPV infection.Follow-up colonoscopy showed no recurrence.To our knowledge this is the first case of a combined minimally invasive treatment of an anal squamous high-grade intraepithelial lesion involving the distal rectum.