Management of gastroparesis refractory to GPOEM by EUS-guided drain associated gastroentero-anastomosis: a new promising option

Abstract Text We present a short series with videocase of patients successfully treated by EUS-GEA with drain assisted technique, for gastroparesis (RG) nonresponding to GPOEM. All patients were followed using GCSI score.Six patients were included, aged 20 to 70 years. The median baseline G-CSI was 4.4 [3.3; 5], the time to recurrence of symptoms was 9 months [0; 48]. Technical success was achieved in 100% of cases, without adverse event.Clinical efficacy rate was 100% after a median follow-up of 6 months [3; 16]. The GCSI at 3 months was [0 0; 2.9], 3 patients had disappearance of symptoms.In conclusion, this report suggests feasibility, safety and efficacy of EUS-guided GEA for managing gastroparesis refractory to all therapies including GPOEM.