First Metastasis Site of Multiple Metastatic Renal Cell Cancer: Bladder

We aimed to present a case report of bladder metastasis in a patient with renal cell cancer (RCC), which is a very rare condition. Bladder metastases from RCC are extremely rare. RCC can metastasize through hematogenous, lymphogenous and urinary tract spread. How RCC metastasizes to the bladder is not clearly understood. Dissemination in the urinary tract or also called antegrade pathway is another form of metastasis to the ureter and bladder. This theory was originally proposed after the detection of tumor cells in the urine of patients with RCC. Tumors confined to the bladder mucosa and recurrent urothelial tumors without metastasis are thought to occur in this way. Approximately 20-30% of patients are metastatic at first but isolated bladder metastases of RCC are very rare and usually accompany multiple metastatic disease. In our case, the metastasis was in the bladder for the first time and in isolation.