Activating a 2×2 Network of hNT Astrocytes with UV Laser Stimulation

Si Li,M. Cather Simpson,E. Scott Graham,Charles P. Unsworth

2019 9th International IEEE/EMBS Conference on Neural Engineering (NER)（2019）

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摘要

To further investigate the communication in astrocytic networks, in vitro astrocytes were patterned in simple networks by using parylene-C/SiO2 platform. We designed a 2×2 small network on parylene-C/SiO2 platform and demonstrated, for the first time, that the intracellular calcium response of a single human hNT astrocyte stimulated by UV laser pulses can be transmitted to neighboring astrocytes in this 2×2 small network. The calcium responses of the astrocytes network were recorded and analyzed.

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关键词

2×2 network,hNT astrocytes,UV laser stimulation,astrocytic networks,simple networks,single human hNT astrocyte,UV laser pulses,neighboring astrocytes,astrocytes network,parylene-C-SiO2 platform,in vitro astrocytes,C

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