Hyperleukocytosis in Acute Myeloid Leukemia: Considerations for Inpatient Diagnosis and Management
CLINICAL JOURNAL OF ONCOLOGY NURSING(2023)
摘要
Hyperleukocytosis, a white blood cell count greater than 100,000/mcl, can be associated with the following three primary oncologic emergencies: leukostasis, disseminated intravascular coagulation, and tumor lysis syndrome. These complications significantly increase a patient's risk of morbidity and mortality. Therefore, timely evidence-based interventions ensure patient safety. This article provides clinical evidence and guidelines for advanced practice nurses working in hematology-oncology to support diagnostic workup and management of hyperleukocytosis in patients with acute myeloid leukemia. A patient case study demonstrates key concepts.
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关键词
hyperleukocytosis,leukostasis,acute myeloid leukemia,tumor lysis syndrome
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