Computational optical sensor with a paper-based peptide panel assay for point-of-care testing of Lyme disease

Hyou-Arm Joung,Rajesh Ghosh, Artem Goncharov, Kevin Ngo, Barath Palanisamy,Elizabeth J. Horn,Paul M. Arnaboldi,Raymond J. Dattwyler,Omai B. Garner,Dino Di Carlo,Aydogan Ozcan

2023 Conference on Lasers and Electro-Optics (CLEO)（2023）

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摘要

We present a computational paper-based optical sensor for point-of-care serodiagnosis of Lyme disease. Using blindly tested human serum samples, we achieved 91.7% sensitivity and 100% specificity against two-tier serology without cross-reactivity from other diseases.

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