Middle-infrared Modulation Of Sleep By Cardiometabolic Function

biorxiv(2023)

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Abstract
The interdependence of sleep and overall well-being is profound. Sleep has the capacity to regulate hematopoiesis, thereby sustaining our physiological equilibrium. Nevertheless, our understanding regarding the potential reversibility of this regulatory process remains limited. In this study, we present evidence suggesting that exposure to middle-infrared radiation (MIR) within the 5-7 mm wavelength range can elicit non-thermal biological effects within the human body. These effects are characterized by an augmentation in blood circulation, mediated through modifications in red blood cell properties. Furthermore, MIR exposure is accompanied by a reduction in homocysteine levels and suppressor T-cell populations. Importantly, daytime modulation of MIR has been shown to significantly facilitate the amelioration of insomnia symptoms during nighttime, primarily through its impact on the architecture of deep sleep. Conclusively, our investigation reveals a robust association between cardiometabolic function and human sleep, with MIR presenting a promising avenue for enhancing sleep quality by regulating both the circulatory system and the immune system. These findings pave the way for the development of therapeutic strategies aimed at mitigating prevalent sleep-related disorders by disentangling the intricate links between sleep and cardiometabolic function. ### Competing Interest Statement The authors have declared no competing interest.
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