Behavioral Outcomes and Neurodevelopmental Disorders Among Children of Women With Epilepsy.

Morris J Cohen,Kimford J Meador,David W Loring,Abigail G Matthews,Carrie Brown,Chelsea P Robalino,Angela K Birnbaum,Paula E Voinescu,Laura A Kalayjian,Elizabeth E Gerard,Evan R Gedzelman,Julie Hanna,Jennifer Cavitt,Maria C Sam,Jacqueline A French,Sean T Hwang,Alison M Pack,Page B Pennell

JAMA neurology（2023）

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摘要

This study suggests that adaptive functioning of children of women with epilepsy taking commonly used ASMs did not significantly differ from that of children of women without epilepsy, but there was an exposure-dependent association of ASMs with functioning. Thus, psychiatric or psychological screening and referral of women with epilepsy and their offspring are recommended when appropriate. Additional research is needed to confirm these findings.

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