Sulforaphene suppresses oesophageal cancer growth through mitogen- and stress-activated kinase 2 in a PDX mouse model.

Chengjuan Zhang,Qiong Wu,Ke Yao,Guoguo Jin,Simin Zhao,Junxia Zhang, Wenjin Zheng,Benling Xu,Yingling Zu,Jing Yuan,Kangdong Liu,Yongjun Guo

American journal of cancer research（2023）

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摘要

The results showed that sulforaphene suppresses ESCC growth in both human oesophageal squamous cells and PDX mouse model by inhibiting MSK2 expression, implicating sulforaphene as a promising candidate for ESCC treatment.

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