Successful treatment of primary mediastinal choriocarcinoma with lung metastasis in a 13-year-old male

PEDIATRIC BLOOD & CANCER(2024)

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Pediatric Blood & CancerEarly View e30765 LETTER TO THE EDITOR Successful treatment of primary mediastinal choriocarcinoma with lung metastasis in a 13-year-old male Jian Li, Jian Li orcid.org/0000-0001-5178-793X Department of Oncology, Children's Hospital of Nanjing Medical University, Nanjing, ChinaSearch for more papers by this authorLulu He, Lulu He Department of Oncology, Children's Hospital of Nanjing Medical University, Nanjing, ChinaSearch for more papers by this authorLi Zhou, Corresponding Author Li Zhou [email protected] Department of Oncology, Children's Hospital of Nanjing Medical University, Nanjing, China Correspondence Tao Li, Department of Oncology, Children's Hospital of Nanjing Medical University, Code 8, Jiangdongnan Road, Nanjing city, Jiangsu province, China. Email: [email protected] Li Zhou, Children's Hospital of Nanjing Medical University, Nanjing 210008, China. Email: [email protected]Search for more papers by this authorTao Li, Corresponding Author Tao Li [email protected] Department of Oncology, Children's Hospital of Nanjing Medical University, Nanjing, China Correspondence Tao Li, Department of Oncology, Children's Hospital of Nanjing Medical University, Code 8, Jiangdongnan Road, Nanjing city, Jiangsu province, China. Email: [email protected] Li Zhou, Children's Hospital of Nanjing Medical University, Nanjing 210008, China. Email: [email protected]Search for more papers by this author Jian Li, Jian Li orcid.org/0000-0001-5178-793X Department of Oncology, Children's Hospital of Nanjing Medical University, Nanjing, ChinaSearch for more papers by this authorLulu He, Lulu He Department of Oncology, Children's Hospital of Nanjing Medical University, Nanjing, ChinaSearch for more papers by this authorLi Zhou, Corresponding Author Li Zhou [email protected] Department of Oncology, Children's Hospital of Nanjing Medical University, Nanjing, China Correspondence Tao Li, Department of Oncology, Children's Hospital of Nanjing Medical University, Code 8, Jiangdongnan Road, Nanjing city, Jiangsu province, China. Email: [email protected] Li Zhou, Children's Hospital of Nanjing Medical University, Nanjing 210008, China. Email: [email protected]Search for more papers by this authorTao Li, Corresponding Author Tao Li [email protected] Department of Oncology, Children's Hospital of Nanjing Medical University, Nanjing, China Correspondence Tao Li, Department of Oncology, Children's Hospital of Nanjing Medical University, Code 8, Jiangdongnan Road, Nanjing city, Jiangsu province, China. Email: [email protected] Li Zhou, Children's Hospital of Nanjing Medical University, Nanjing 210008, China. Email: [email protected]Search for more papers by this author First published: 12 November 2023 https://doi.org/10.1002/pbc.30765 Li Zhou and Tao Li are equal corresponding authors. Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat No abstract is available for this article. REFERENCES 1Zhang S, Gao H, Wang XA, et al. Primary choriocarcinoma in mediastinum with multiple lung metastases in a male patient: a case report and a review of the literature. Thorac Cancer. 2014; 5(5): 463-467. 2Pan W, Hou J. Pembrolizumab for treatment of a male with primary mediastinal choriocarcinoma: a case report. Transl Cancer Res. 2022; 11(9): 3416-3420. 3El-Zaatari ZM, Ro JY. Mediastinal germ cell tumors: a review and update on pathologic, clinical, and molecular features. Adv Anat Pathol. 2021; 28(5): 335-350. 4Gaude GS, Patil P, Malur PR, et al. Primary mediastinal choriocarcinoma. South Asian J Cancer. 2013; 2(2): 79. 5Qiu Z, Wu Y, Wang Y, Hu C. Male primary mediastinal choriocarcinoma with diffuse metastases: a case report. Medicine (Baltimore). 2019; 98(28):e16411. 6Lu WG, Ye F, Shen YM, et al. EMA-CO chemotherapy for high-risk gestational trophoblastic neoplasia: a clinical analysis of 54 patients. Int J Gynecol Cancer. 2008; 18(2): 357-362. 7Bokemeyer C, Kollmannsberger C, Meisner C, et al. First-line high-dose chemotherapy compared with standard-dose PEB/VIP chemotherapy in patients with advanced germ cell tumors: a multivariate and matched-pair analysis. J Clin Oncol. 1999; 17(11): 3450-3456. 8Murshed KA, Kanbour A, Akhtar M, Al Hyassat S. Primary mediastinal choriocarcinoma presenting as cutaneous metastasis with resistance to chemotherapy: case report and literature review. J Cutan Pathol. 2021; 48(1): 81-85. 9Wang H, Chen X, Zhang R. Primary mediastinal choriocarcinoma in an 18-year-old male with pulmonary and brain metastasis: a case report. Clin Respir J. 2023; 17(10): 1082-1087. 10Ghorani E, Kaur B, Fisher RA, et al. Pembrolizumab is effective for drug-resistant gestational trophoblastic neoplasia. Lancet. 2017; 390(10110): 2343-2345. 11Cheng HY, Yang JJ, Zhao J, et al. Preliminary study of PD-1 inhibitor in the treatment of drug-resistant recurrent gestational trophoblastic neoplasia. Zhonghua Fu Chan Ke Za Zhi. 2020; 55(6): 390-394. 12Han C, Zhou Y, Ma JA, Liu J, Jiang YN, Zhang HX. A promising treatment option for refractory male primary choriocarcinoma: report of two cases. Transl Cancer Res. 2020; 9(4): 3054-3060. 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