Re: David D’Andrea, Francesco Soria, Rodolfo Hurle, et al. En Bloc Versus Conventional Resection of Primary Bladder Tumor (eBLOC): A Prospective, Multicenter, Open-label, Phase 3 Randomized Controlled Trial. Eur Urol Oncol. In press. https://doi.org/10.1016/j.euo.2023.07.010

We read with great interest the article by D’Andrea et al. [ [1] D’Andrea D, Soria F, Hurle R, et al. En bloc versus conventional resection of primary bladder tumor (eBLOC): a prospective, multicenter, open-label, phase 3 randomized controlled trial. Eur Urol Oncol. In press. https://doi.org/10.1016/j.euo.2023.07.010. Google Scholar ] comparing en bloc (eTURB) versus conventional (cTURB) resection of primary bladder tumor. We commend the authors for their valuable investigation into an interesting topic in the field of bladder cancer for which the current quality of evidence leaves room for further exploration [ [2] Teoh J.Y.C. MacLennan S. Chan V.W.S. et al. An international collaborative consensus statement on en bloc resection of bladder tumour incorporating two systematic reviews, a two-round Delphi survey, and a consensus meeting. Eur Urol. 2020; 78: 546-569https://doi.org/10.1016/j.eururo.2020.04.059 Abstract Full Text Full Text PDF PubMed Scopus (69) Google Scholar ]. The study by D’Andrea et al. [ [1] D’Andrea D, Soria F, Hurle R, et al. En bloc versus conventional resection of primary bladder tumor (eBLOC): a prospective, multicenter, open-label, phase 3 randomized controlled trial. Eur Urol Oncol. In press. https://doi.org/10.1016/j.euo.2023.07.010. Google Scholar ] used data from randomized patient cohorts, which ensures high reliability of the results. Moreover, the study design is very clear, with a rigorous statistical methodology applied.