1169 AZD5863: a specific, potent, affinity-optimized claudin 18.2 and CD3 binding T cell-engager that elicits low cytokine release and is capable of bystander killing Rakesh Kumar , Yun He , Simon Dovedi , Mark Cobbold , Kristen Pollizzi , Saso Cemerski , Scott Hammond , Marina Natoli , Yiping Rong , Jonathan Fitzgerald , Mary McFarlane , Kathy Mulgrew , Miguel Gaspar , Christopher Lloyd , Douglas C Palmer , Maria AS Broggi , Laure Castan , Sharif Rahmy , Cathryn Kelton , Martin Korade , Oisin Huhn , D Gareth Rees , Anna Sigurdardottir , Benjamin Ridgway , Kathryn Ball , Fred Arce Vargas , Natalia Ceaicovscaia , Gayle Pouliot , Philip Szekeres Journal for ImmunoTherapy of Cancer（2023）
关键词
claudin, low cytokine release, azd5863, cd3, affinity-optimized, cell-engager
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