Identification of prognostic biomarkers for antibiotic associated nephrotoxicity in cystic fibrosis

Andrew Hart,Francine Cesar,Leila R Zelnick, Nick O'Connor, Zoie Bailey, Jordan Lo, Kirk Van Ness,Ian B. Stanaway,Theo K. Bammler,James W. MacDonald,Matthew R. Thau,Jonathan Himmelfarb,Christopher H. Goss,Moira Aitken,Edward J. Kelly,Pavan K. Bhatraju

Journal of Cystic Fibrosis（2023）

引用 0|浏览19

暂无评分

摘要

•Repeated use of antibiotics to treat pulmonary exacerbations may lead to kidney injury.•We lack early urinary biomarkers to recognize kidney injury.•Using a kidney-on-a-chip and a CF cohort, we identify new urinary biomarkers of kidney injury.•Urinary soluble Fas, a marker of apoptosis, was associated with chronic kidney disease in CF.

查看译文

关键词

Nephrotoxicity,Chronic kidney injury,Urinary biomarkers

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要