Fazirsiran reduces liver Z-alpha-1 antitrypsin synthesis, decreases globule burden and improves histological measures of liver disease in adults with alpha-1 antitrypsin deficiency: a randomized placebo-controlled phase 2 study

Virginia Clark, Charlton Strange, Pavel Strnad, Antonio Sanchez, Paul Yien Kwo, Vitor Magno Pereira, Bart Van Hoek, Igor Barjaktarevic, Angelo Guido Corsico, Monica Pons, Monica Goldklang, Meagan Gray, Brooks Kuhn, Hugo Vargas, John M. Vierling, Raj Vuppalanchi, Mark Brantly, Naomi Kappe, Ting Chang, Thomas Schluep, Min Yi, James Hamilton, Javier San Martin, Rohit Loomba

JOURNAL OF HEPATOLOGY（2023）

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