Fucoidan-based coating on magnesium alloy improves the hemocompatibility and pro-endothelialization potential for vascular stent application

MATERIALS & DESIGN(2023)

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摘要
•MgF2 layer, PDA layer and fucoidan in the coating can significantly enhance the corrosion resistance of ZE21B alloy.•Low fucoidan grafting density promoted the proliferation and migration of endothelial cells.•Fucoidan-based coating inhibited intimal hyperplasia and promote rapid endothelialization in vivo.
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关键词
Magnesium alloy stent,Surface modification,Fucoidan,Hemocompatibility,Endothelialization
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