Preconception Antidiabetic Drugs in Men and Birth Defects in Offspring: A Nationwide Cohort Study

OBSTETRICAL & GYNECOLOGICAL SURVEY(2022)

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摘要
(Abstracted from Ann Intern Med 2022;175:665-673) Diabetes mellitus is known to compromise sperm quality and is associated with impaired male fertility. Metformin is a first-line oral diabetes medication that has been shown to improve markers of semen quality in obese men but reduces serum testosterone levels independently of glycemic control.
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关键词
birth defects,cohort study,offspring
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