Development of a porous reduced graphene oxide modified electrode for simultaneous determination of dopamine and uric acid

Porous reduced graphene oxide (pr-GO) exhibits good electrical conductivity, higher surface area and higher sensitivity. Herein, we have synthesized pr-GO by solution combustion method and characterized by XRD, FT-IR, SEM, Raman and absorption spectral studies used for the simultaneous determination of dopamine (DA) and uric acid (UA). The pr-GO-modified electrode showed good electrocatalytic activity and separated well the oxidation peaks of DA and UA. A simple and sensitive differential pulse voltammetric method was proposed for the simultaneous determination of DA and UA in the range of 0.5–470.8 µM and 0.1–450.1 µM, respectively, at pr-GO-modified electrode with LOD ( s / n = 3) values of 0.031 µM and 0.060 µM for DA and UA, respectively.