A systematic review exploring the mechanisms by which citrus bioflavonoid supplementation benefits blood glucose levels and metabolic complications in type 2 diabetes mellitus

•Diabetic patients may need new, better optimized treatment options.•Bioflavonoids are polyphenolic compounds available in a range of commercial citrus bioflavonoid supplements.•Citrus bioflavonoid supplements contain variable concentrations of citrus compounds.•Bioflavonoids are known for their antioxidant properties and hence are a good additional treatment option.