How Does Target Lesion Selection Affect RECIST? A Computer Simulation Study.

Teresa M Tareco Bucho,Renaud L M Tissier,Kevin B W Groot Lipman,Zuhir Bodalal,Andrea Delli Pizzi,Thi Dan Linh Nguyen-Kim, Regina G H Beets-Tan,Stefano Trebeschi

Investigative radiology（2023）

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摘要

Our results demonstrate that RECIST can deliver an accurate estimate of TTB in localized disease, but fails in cases of distal metastases and multiple organ involvement. This is worsened by the "selection of the largest lesions," which introduces a bias that makes it hardly possible to perform an accurate estimate of the TTB. Including more (if not all) lesions in the quantitative analysis of tumor burden is desirable.

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