Super-resolution microscopy: Insights into mitochondria-lysosome crosstalk in health and disease
JOURNAL OF CELL BIOLOGY(2023)
Abstract
Live super-resolution microscopy has allowed for new insights into recently identified mitochondria-lysosome contact sites, which mediate crosstalk between mitochondria and lysosomes, including co-regulation of Rab7 GTP hydrolysis and Drp1 GTP hydrolysis. Here, we highlight recent findings and future perspectives on this dynamic pathway and its roles in health and disease.
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