Use of Acitretin Among Girls and Women of Childbearing Age and Occurrence of Acitretin-Exposed Pregnancies in Germany.

Jonas Reinold,Bianca Kollhorst,Hellen L Temme,Nadine Wentzell,Ulrike Haug

Clinical drug investigation（2023）

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摘要

We observed 35 acitretin-exposed pregnancies mainly because treatment ended too late before pregnancy. Approximately one in five children born from these pregnancies had malformations, highlighting the importance of drawing more attention to the long-lasting teratogenicity of this drug.

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