Skin-limited Langerhans Cell Histiocytosis in an Adult Presenting As Isolated, Eroded, “kissing” Intergluteal Plaques
JAAD case reports(2023)
Abstract
Langerhans cell histiocytosis (LCH) is characterized by clonal proliferation of histiocytes accumulating in a variety of organs, most often the skin, bone, lungs, and pituitary gland.1,2 Although LCH is most commonly observed in children, it can rarely affect adults.3 While LCH can be skin-limited, most patients with cutaneous disease have multisystem involvement, which is associated with poorer prognosis.2 We report a case of an adult man with a history of liver transplant presenting with an intergluteal rash that was diagnosed as cutaneous LCH.
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Key words
intergluteal cleft erosion,Langerhans cell histiocytosis
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