Plethysmograph Variability Index Values in Healthy Neonates – An Observational Pilot Study

Objectives To establish normative data of plethysmograph variability index (PVI), a simple non-invasive tool to measure fluid responsiveness, in neonates. Methods All healthy term and late preterm neonates were enrolled. PVI was recorded by pulse-oximeter on first three days of life along with other vital parameters. Data was analysed using SPSS software. Results The median PVI value was noted to be 21 with a wide range. The distribution of PVI did not differ according to day of life/ gestational age/ gender/ weight for gestational age. It did not significantly correlate with heart rate, gestational age or birth weight. A weak positive correlation was noted between PVI and PI (Rho = 0.157, p <0.001). Conclusions PVI normative data in neonates has been presented. Serial trend of PVI values is more useful than a single value in making clinical decisions.